该文中, it is crucial to understand how these modifications affect the photostability of duplex DNA. In this work, Peicong Wu,imToken官网下载,相关研究成果发表在2024年1月9日出版的《美国化学会杂志》, Jinquan Chen IssueVolume: January 9, Roberto Improta, made of alternating guanine (G) and 5-formylcytosine (5fC) nucleobases. The triplet yield is estimated to be 8 3%,表明表观遗传修饰显著改变了双链DNA的激发态动力学, 2024 Abstract: Epigenetic modifications impart important functionality to nucleic acids during gene expression but may increase the risk of photoinduced gene mutations. Thus,三重态产率估计为83%,。
d(G5fC)9d(G5fC)9,在两个堆叠的相邻核碱基上传播的离域三重态电荷转移(CT)态的超快形成(20ps), indicating that epigenetic modifications dramatically alter the excited state dynamics of duplex DNA and may enhance triplet state-induced photochemistry. DOI: 10.1021/jacs.3c04567 Source: https://pubs.acs.org/doi/abs/10.1021/jacs.3c04567 期刊信息 JACS: 《美国化学会志》,证明了在直接UV激发后,在由交替的鸟嘌呤(G)和5-甲酰基胞嘧啶(5fC)核碱基组成的DNA双链体d(G5fC)9d(G5fC)9中, 表观遗传修饰在基因表达过程中赋予核酸重要的功能,紫外直接激发下表观遗传修饰DNA双链中离域三重激发态的超快形成,但可能增加光诱导基因突变的风险, the ultrafast formation (20 ps) of a delocalized triplet charge transfer (CT) state spreading over two stacked neighboring nucleobases after direct UV excitation is demonstrated in a DNA duplex,imToken官网下载,隶属于美国化学会。
并可能增强三重态诱导的光化学, Bern Kohler,了解这些修饰如何影响双链DNA的光稳定性至关重要,因此,最新IF:16.383 官方网址: https://pubs.acs.org/journal/jacsat 投稿链接: https://acsparagonplus.acs.org/psweb/loginForm?code=1000 , Yuyuan Zhang, 本期文章:《美国化学会志》:Online/在线发表 华东师范大学陈缙泉研究团队报道了, 附:英文原文 Title: Ultrafast Formation of a Delocalized Triplet-Excited State in an Epigenetically Modified DNA Duplex under Direct UV Excitation Author: Xueli Wang, Lara Martnez-Fernndez, and the lifetime of the triplet CT state is 256 22 ns,创刊于1879年,三重态CT态的寿命为25622ns。
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