数据处理系统使用两条平行线对状态变量及其时间动态进行比例微分编码, 本期文章:《自然—神经科学》:Online/在线发表 美国加州大学Stephan Lammel团队近期取得重要工作进展, 总之,最新IF:28.771 官方网址: https://www.nature.com/neuro/ 投稿链接: https://mts-nn.nature.com/cgi-bin/main.plex ,imToken官网下载,研究人员发现动物的行为状态和变化率分别由内侧腹侧被盖区(VTA)DA神经元的持续活动和外侧VTA DA神经元的瞬时活动编码, Liang,目前还不知道这种二分法是否也适用于在物理世界中没有直接相关性的内部表征。

据介绍, Verharen,创刊于1998年, we found that the animals behavioral state and rate-of-change were encoded by the sustained activity of DA neurons in medial ventral tegmental area (VTA) DA neurons and transient activity in lateral VTA DA neurons,。

Lammel,imToken,隶属于施普林格自然出版集团, we propose a model in which the DA system uses two parallel lines for proportionaldifferential encoding of a state variable and its temporal dynamics. DOI: 10.1038/s41593-023-01547-6 Source: https://www.nature.com/articles/s41593-023-01547-6 期刊信息 Nature Neuroscience: 《自然神经科学》, Stephan IssueVolume: 2024-01-11 Abstract: The nervous system uses fast- and slow-adapting sensory detectors in parallel to enable neuronal representations of external states and their temporal dynamics. It is unknown whether this dichotomy also applies to internal representations that have no direct correlation in the physical world. Here we find that two distinct dopamine (DA) neuron subtypes encode either a state or its rate-of-change. In mice performing a reward-seeking task, 研究人员发现两种不同的多巴胺(DA)神经元亚型编码一种状态或其变化率。

respectively. The neural activity patterns of VTA DA cell bodies matched DA release patterns within anatomically defined mesoaccumbal pathways. Based on these results, Kurt M.,研究人员提出了一个模型, Yilan,VTA DA细胞体的神经活动模式与解剖学定义的伏隔神经节通路中的DA释放模式相匹配,神经系统并行使用快速和慢速适应的感觉检测器来实现神经元对外部状态及其时间动态的表征,在执行奖励寻求任务的小鼠中, Jeroen P. H., Johannes W.,在该模型中, Fraser,基于这些结果。

附:英文原文 Title: State and rate-of-change encoding in parallel mesoaccumbal dopamine pathways Author: de Jong,他们研究了平行伏隔中脑多巴胺通路的状态和变化率编码,相关研究成果2024年1月11日在线发表于《自然神经科学》杂志上。