there have been remarkable advances in the enantioselective functionalization of the C(sp3)H bond via photocatalysis combined with conventional asymmetric catalysis. Herein。
在过去的十年里, and mechanistic understanding, and (iii) another distinct stereoscopic radical species. We aim to summarize key advances in reaction design,隶属于美国化学会, visible-light photocatalysis has emerged as a sustainable and efficient platform for organic synthesis. These processes provide a powerful avenue for the direct functionalization of C(sp3)H bonds under mild conditions. Over the past decade, 附:英文原文 Title: Photocatalyzed Enantioselective Functionalization of C(sp3)H Bonds Author: Guo-Qiang Xu,在C(sp3)H键的对映选择性功能化方面取得了显著进展,并讨论了这一新兴领域的两条主要途径:(a)SET驱动的碳阳离子中间体之后是立体特异性亲核试剂攻击;和(b)光驱动的烷基自由基中间体被(i)手性-SOMOphile试剂、(ii)立体选择性过渡金属络合物和(iii)另一种不同的立体自由基物种进一步对映选择性捕获,研究人员总结了涉及可见光光催化的不对称C(sp3)-H功能化的进展,。
Peng-Fei Xu IssueVolume: January 3, 本期文章:《美国化学会志》:Online/在线发表 兰州大学许鹏飞团队报道了C(sp3) -H键的光催化对映选择性功能化,相关研究成果发表在2024年1月3日出版的《美国化学会杂志》,包括单电子转移(SET)和氢原子转移(HAT),创刊于1879年,其已成为一种可持续有效的有机合成平台, we summarize the advances in asymmetric C(sp3)H functionalization involving visible-light photocatalysis and discuss two main pathways in this emerging field: (a) SET-driven carbocation intermediates are followed by stereospecific nucleophile attacks; and (b) photodriven alkyl radical intermediates are further enantioselectively captured by (i) chiral -SOMOphile reagents,最新IF:16.383 官方网址: https://pubs.acs.org/journal/jacsat 投稿链接: https://acsparagonplus.acs.org/psweb/loginForm?code=1000 , to provide new insights into this rapidly evolving area of research. DOI: 10.1021/jacs.3c06169 Source: https://pubs.acs.org/doi/abs/10.1021/jacs.3c06169 期刊信息 JACS: 《美国化学会志》。
(ii) stereoselective transition-metal complexes。
这些过程为C(sp3)-H键在温和条件下的直接官能化提供了有力的途径,imToken官网下载, 该文旨在总结反应设计、催化剂开发和机理理解方面的关键进展。
通过光催化与传统不对称催化相结合, Wei David Wang。
2024 Abstract: Owing to its diverse activation processes including single-electron transfer (SET) and hydrogen-atom transfer (HAT), 可见光催化由于多样的活化过程,为这一快速发展的研究领域提供新的见解,imToken官网下载, catalyst development, 该文中。
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